Table 2.
Expression of BA receptors that regulate cardiovascular function.
| BA receptors | Tissue type | Direct BA action demonstrated | References |
|---|---|---|---|
| Nuclear receptors | |||
| FXR | Endothelial cells | Yes | 17, 72 |
| Vascular smooth muscle cells | Yes | 74, 75, 76 | |
| Cardiomyocytes | No | 17 | |
| PXR | Mesenteric arteries | No | 24 |
| VDR | Cardiomyocytes | No | 49 |
| G‐Protein‐coupled Receptors | |||
| TGR5 | Hepatic sinusoidal endothelial cells | Yes | 33 |
| Cardiomyocytes | No | 34 | |
| M2R | Cardiomyocytes | Yes | 30 |
| M3R | Endothelial cells | Yes | 66 |
| Potassium channels | |||
| BKCa | Vascular smooth muscle cells | Yes | 36, 63 |