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. Author manuscript; available in PMC: 2013 Jul 9.
Published in final edited form as: J Ethnopharmacol. 2010 Mar 19;129(2):220–226. doi: 10.1016/j.jep.2010.03.008

Fig. 2. GTP shift of Compound 1 binding to 5-HT7 receptors.

Fig. 2

Binding of Compound 1 to the human 5-HT7 receptor in the presence of [3H]LSD and in the presence or absence of GTP (100 μM). The addition of GTP resulted in a right-hand shift of the IC50 curve, indicating that the compound acts as an agonist of the 5-HT7 receptor.