Table 4.

Summary of computational considerations, associated physiological references, and applicable computational studies related to patient-specific modeling for CoA

Consideration	Physiologic reference(s)	Applicable computational reference(s)	Currently implemented
Replication of physiologic flow patterns and aortic root motion	32	39	partially
Outflow boundary conditions that replicate the distal vasculature to reproduce flow splits and BP	40	12	yes
Compliance of the aorta, variable tissue properties and support structures for the arterial system	41, 42	23, 26, 43	partially
Inclusion of intercostal, internal mammary and collateral vessels	44, 45	46	partially
Ability to provide unique, clinically applicable data	47	4	yes