Figure 5.

Summary of sex-steroid metabolism in men. Geographical and racial differences in serum sex steroids in elderly men are indicated in red. 3α-DIOL-3G, androstane-3α,17β-diol-3glucuronide; 3α-DIOL-17G, androstane-3α,17β-diol-17glucuronide; 4-dione, androstenedione; 5-Diol, androst-5-ene-3β,17β-diol; A-dione, androstanedione; ADT, androsterone; ADT-G, ADT glucuronide; DHEA, dehydroepiandrosterone; DHT, dihydrotestosterone; E2, estradiol; E1, estrone; E1-S, estrone sulfate; HSD, hydroxysteroid dehydrogenase; UGT, uridine glucuronosyl transferase. (Adapted from Orwoll et al.59 with permission from the Endocrine Society.)