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. Author manuscript; available in PMC: 2013 Jul 9.
Published in final edited form as: Breast Cancer Res Treat. 2012 Mar 29;134(3):1041–1055. doi: 10.1007/s10549-012-1992-x

Fig 1.

Fig 1

Effect of GR-24 on breast cancer cell line proliferation. MDA-MB-231, MDA-MB-436, MCF-7 and BJ ‘normal’ fibroblasts were exposed to varying concentrations of GR-24 for up to 10 days. At the indicated time points, plates were stained with crystal violet. Data are reported as the Percent Absorbance (560nm) of vehicle control. Average ± standard deviations (SD). Student's t-test (2-tailed, paired) was used to evaluate GR-24 treated groups with vehicle (control) groups at final time point and regarded as being significant if p < 0.05 (*), very significant if p<0.01 (**), extremely significant if p<0.001 (***). (B) Graph showing the light absorbance reading (560nm) after 7 days exposure to the indicated doses of GR-24. Data expressed as a percentage of vehicle controls. Average of triplicate samples ± SD. Horizontal line (---) marks 50% reduction in Absorbance (560nm) relative to vehicle controls. Right, Table showing inhibitory concentrations required for 50% reduction in growth after 7days (IC50/72d), and calculated by performing linear regression with interpolation between relevant y-axis data points (GraphPad Prism Software).