TABLE 3.

Median Akep (1/s) values of GMM-classified and thresholded tumor microenvironments of perfused, hypoxic and necrotic areas.

Tumor slices	Perfused area from DCE-GMM	Perfused area from thresholding of standard images	Hypoxic area from DCE- GMM	Hypoxic area from thresholding of standard images	Necrotic area from DCE- GMM	Necrotic area from thresholding of standard images
Tumor 3(sl.1, 1240 mm3):Training	0.0168±0. 0079	0.0174±0. 0138	0.0036±0 .0114	0.004±0. 0.0027	0.0020±0 .0092	0.0018±0. 0022
Tumor 3(sl.2, 1240 mm3)	0.0121±0. 0068	0.0123±0. 0161	0.0024±0 .0124	0.0015±0. 0.0007	0.0015±0 .0087	0.0007±0. 0007
Tumor 3(sl.3, 1240 mm3 mm3)	0.0065±0. 0029	0.0090±0. 0096	0.0021±0 .0009	0.0013±0. 0009	0.0020±0 .0085	0.0004±0. 0006
Tumor 4 (sl.1,870 mm3)	0.0095±0. 0100	0.0122±0. 0130	0.0028±0 .0060	0.0013±0. 0008	0.0024±0 .0100	0.0009±0. 0008
Tumor 4(sl.2,870 mm3)	0.0088±0. 0089	0.0105±0. 0110	0.0036±0 .0073	0.0013±0. 0009	0.0007±0 .0050	0.0008±0 0008.
Tumor 5(sl.1,720 mm3)	0.0089±0. 0029	0.0107±0. 0020	0.0065±0 .0021	0.0064±0. 0036	0.0017±0 .0009	0.0051±0. 0036
Tumor 5(sl.2,720 mm3)	0.0081±0. 0020	0.0106±0. 0014	0.0048±0 .0015	0.0045±0. 0023	0.0016±0 .0011	0.0029±0. 0022
Median±S D	0.0101±0. 0059	0.0118±0. 0096	0.0037±0 .006	0.0030±0. 0017	0.0017±0 .0062	0.0018±0. 0016