. Author manuscript; available in PMC: 2014 May 1.

Published in final edited form as: NMR Biomed. 2013 Feb 25;26(5):519–532. doi: 10.1002/nbm.2888

TABLE 4.

The spatial percentage overlap of perfused, hypoxic, and necrotic tumor areas obtained by GMM-based classification, K^trans and IAUC thresholding with those obtained from Ak_ep, pimonidazole, and H&E images for tumor 3 (slice1) and tumor 4 (slice1).

Classification methods and tumor slices		% overlap of perfused area		% overlap of hypoxic area		% overlap of necrotic area		% overlap of extended necrotic area
Classification methods and tumor slices		OL1	OL2	OL1	OL2	OL1	OL2	OL1	OL2
GMM classification	Tumor 3 (slice1)	0.90	0.81	0.70	0.36	0.58	0.56	0.50	0.91
GMM classification	Tumor 4 (slice1)	0.86	0.88	0.67	0.75	0.72	0.57	0.57	0.77
K^trans thresholding	Tumor 3 (slice1)	0.87	0.68	0.58	0.34	0.58	0.55	0.49	0.89
K^trans thresholding	Tumor 4 (slice1)	0.61	0.59	0.35	0.43	0.68	0.37	0.69	0.60
IAUC thresholding	Tumor 3 (slice1)	0.83	0.86	0.55	0.32	0.58	0.46	0.57	0.84
IAUC thresholding	Tumor 4 (slice1)	0.82	0.29	0.03	0.25	0.00	0.00	0.01	0.06