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. 2013 Jun 20;14:26. doi: 10.1186/1471-2172-14-26

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Copyright © 2013 Nakanjako et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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CD4 and CD8 T-cell proliferation up stimulation by SEB, PPD, GagA&D and CMV antigens respectively; among suboptimal (SO) relative to optimal (OP) immune responders after 4 years of suppressive antiretroviral therapy. Panel A shows lower CD4 and CD8 proliferation among suboptimal relative to optimal responders upon SEB stimulation, Panel B shows lower CD8 proliferation among suboptimal relative to optimal responders upon stimulation with tuberculin PPD, Panel C shows lower CD4 proliferation upon stimulation with Gag A & D although the difference is not statistically significant and Panel D shows lower CD4 proliferation upon stimulation with CMV although the difference is not statistically significant.