Table 1.
Isolates | Patient | Sample origina | STs | acsA | aroE | guaA | mutL | nuoD | ppsA | trpE | Antibiotic patternb |
---|---|---|---|---|---|---|---|---|---|---|---|
PaC1 |
1 |
W |
ST-1138* |
5 |
3 |
79 |
5 |
1 |
7 |
47 |
XDR |
PaC49 |
1 |
RS |
ST-1191* |
45 |
148* |
15 |
35 |
53 |
106* |
3 |
MDR |
PaC51 |
1 |
RS |
ST-1147* |
17 |
3 |
5 |
3 |
1 |
6 |
26 |
non-MDR |
PaC52 |
1 |
W |
ST-1138* |
5 |
3 |
79 |
5 |
1 |
7 |
47 |
XDR |
PaC2 |
2 |
W |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC3 |
3 |
R |
ST-235 |
38 |
11 |
3 |
13 |
1 |
2 |
4 |
non-MDR |
PaC4 |
4 |
R |
ST-800 |
17 |
22 |
11 |
3 |
3 |
15 |
3 |
non-MDR |
PaC5 |
5 |
W |
ST-108 |
39 |
5 |
20 |
5 |
1 |
6 |
31 |
XDR |
PaC7 |
6 |
R |
New-1 |
28 |
5 |
36 |
- |
3 |
13 |
7 |
MDR |
PaC16 |
6 |
R |
New-2 |
28 |
5 |
20 |
- |
3 |
13 |
7 |
MDR |
PaC9 |
7 |
U |
ST-274 |
23 |
5 |
11 |
7 |
1 |
12 |
7 |
XDR |
PaC10 |
8 |
U |
ST-1139* |
28 |
22 |
20 |
3 |
3 |
14 |
19 |
XDR |
PaC19 |
8 |
U |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC32 |
8 |
RS |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC40 |
8 |
R |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC11 |
9 |
U |
ST-235 |
38 |
11 |
3 |
13 |
1 |
2 |
4 |
XDR |
PaC24 |
9 |
U |
ST-235 |
38 |
11 |
3 |
13 |
1 |
2 |
4 |
XDR |
PaC12 |
10 |
R |
ST-1140* |
38 |
11 |
20 |
13 |
1 |
2 |
4 |
XDR |
PaC14 |
11 |
R |
ST-1141* |
113 |
4 |
5 |
67 |
1 |
17 |
26 |
non-MDR |
PaC15 |
12 |
R |
ST-1142* |
35 |
11 |
112 |
16 |
1 |
6 |
42 |
MDR |
PaC17 |
13 |
R |
ST-1186* |
39 |
5 |
20 |
59* |
1 |
20 |
15 |
non-MDR |
PaC18a |
14 |
U |
ST-1143* |
8 |
5 |
9 |
3 |
1 |
4 |
9 |
non-MDR |
PaC18b |
14 |
U |
ST-1143* |
8 |
5 |
9 |
3 |
1 |
4 |
9 |
non-MDR |
PaC20 |
15 |
U |
ST-1144* |
39 |
10 |
1 |
3 |
4 |
6 |
7 |
non-MDR |
PaC21 |
16 |
R |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC23 |
17 |
U |
ST-1187* |
35 |
22 |
5 |
3 |
1 |
104* |
4 |
non-MDR |
PaC25a |
18 |
U |
ST-207 |
47 |
4 |
5 |
33 |
1 |
6 |
40 |
non-MDR |
PaC25b |
18 |
U |
ST-207 |
47 |
4 |
5 |
33 |
1 |
6 |
40 |
non-MDR |
PaC26 |
19 |
R |
ST-235 |
38 |
11 |
3 |
13 |
1 |
2 |
4 |
XDR |
PaC27 |
20 |
R |
ST-274 |
23 |
5 |
11 |
7 |
1 |
12 |
7 |
non-MDR |
PaC28 |
21 |
U |
ST-1188* |
69* |
147* |
5 |
11 |
2 |
15 |
2 |
MDR |
PaC29 |
22 |
R |
ST-1145* |
15 |
5 |
1 |
1 |
1 |
12 |
1 |
non-MDR |
PaC30 |
23 |
PS |
ST-244 |
17 |
5 |
12 |
3 |
14 |
4 |
7 |
non-MDR |
PaC31 |
24 |
U |
ST-499 |
11 |
5 |
7 |
27 |
2 |
7 |
33 |
MDR |
PaC33 |
25 |
R |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC34 |
26 |
R |
ST-179 |
36 |
27 |
28 |
3 |
4 |
13 |
7 |
MDR |
PaC35 |
27 |
U |
ST-235 |
38 |
11 |
3 |
13 |
1 |
2 |
4 |
MDR |
PaC36a |
28 |
R |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC36b |
28 |
R |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
MDR |
PaC37 |
29 |
B |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC38 |
29 |
B |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC39 |
30 |
U |
ST-508 |
15 |
5 |
11 |
3 |
2 |
4 |
3 |
non-MDR |
PaC41 |
31 |
U |
ST-1189* |
72* |
5 |
11 |
72 |
3 |
105* |
3 |
non-MDR |
PaC42 |
32 |
W |
ST-253 |
4 |
4 |
16 |
12 |
1 |
6 |
3 |
MDR |
PaC56 |
32 |
B |
ST-253 |
4 |
4 |
16 |
12 |
1 |
6 |
3 |
MDR |
PaC43 |
33 |
R |
ST-235 |
38 |
11 |
3 |
13 |
1 |
2 |
4 |
XDR |
PaC44 |
34 |
U |
ST-316 |
13 |
8 |
9 |
3 |
1 |
6 |
9 |
non-MDR |
PaC45 |
35 |
U |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC46 |
36 |
R |
ST-1190* |
45 |
148* |
15 |
35 |
53 |
106* |
19 |
MDR |
PaC47 |
37 |
R |
ST-175 |
28 |
22 |
5 |
3 |
3 |
14 |
19 |
XDR |
PaC48 |
38 |
R |
ST-253 |
4 |
4 |
16 |
12 |
1 |
6 |
3 |
non-MDR |
PaC54 |
38 |
R |
ST-253 |
4 |
4 |
16 |
12 |
1 |
6 |
3 |
non-MDR |
PaC50 |
39 |
US |
ST-1146* |
5 |
11 |
57 |
33 |
1 |
6 |
3 |
non-MDR |
PaC53 |
40 |
U |
ST-1148* |
16 |
5 |
12 |
3 |
2 |
1 |
18 |
non-MDR |
PaC55 |
41 |
R |
ST-179 |
36 |
27 |
28 |
3 |
4 |
13 |
7 |
non-MDR |
PaC57 | 42 | R | ST-1149* | 18 | 11 | 57 | 5 | 1 | 20 | 26 | non-MDR |
Asterisk mark (*) indicates the new alleles, new alleles combinations, and new sequence types described in this study. -, gene not amplified/sequenced.
aSample origin: blood (B), wound (W), urine (U), respiratory (R), rectal smear (RS), urethral smear (US), prepuce smear (PS).
bThe isolates were classified according to the resistance pattern, as multidrug-resistant (MDR, non-susceptible to ≥1 agent in ≥3 antibiotic categories), extensively drug-resistant (XDR, non-susceptible to ≥ 1 agent in all but ≤2 antibiotic categories) and non-multidrug resistant (non-MDR).