Figure 2. 50 µM resveratrol is toxic to C₂C₁₂ myotubes.

(A) Exposure to 50 µM resveratrol (RSV) for 24 h is toxic to C₂C₁₂ myotubes resulting in a decrease in viable cells and (B) a decrease in ATP content. Values are means ± SE for 4–6 experiments. (C) PGC-1α overexpression in C₂C₁₂ myotubes protects against the toxic effect of 24 h exposure to 50 µM RSV on viability and (D) ATP content. Values are means ± SE for six experiments. *p<0.05 versus basal.