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View full-text article in PMC

. 2013 Jun 5;10:59. doi: 10.1186/1742-4690-10-59

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Copyright © 2013 Manoussaka et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Analysis of peripheral blood gut-homing α4⁺β7⁺T_CMand T_EMpopulations. Subsets were defined on expression of CD28 within the CD95⁺ T cell population before and after infection under different conditions of replication permissivity. (a) Representative result illustrating the gating strategy. Comparison of frequencies of global, gut-homing, T_CM and T_EM CD4⁺ (b &c) and CD8⁺ (d &e) T cell populations before and after chronic SIV infection. Statistically significant differences are shown as ρ values determined by paired t-test.