Table 1.
Proviral DNA loads in tissues
| Animal No. |
SIV DNA copies / 105 MNC |
|||||
|---|---|---|---|---|---|---|
|
SlV-rtTA∆nef |
SlV∆nef |
|||||
|
Dox withdrawn |
Dox maintained |
|||||
| E62 | E64 | E69 | E72 | E74 | E78 | |
| PBMC |
<1a |
<1 |
1.37 |
<1 |
2.59 |
2.63 |
| Spleen |
1.79 |
2.47 |
10.3 |
8.02 |
95.0 |
25.83 |
| Peripheral LNb |
<1 |
1.46 |
12.1 |
88.4 |
50.1 |
50.3 |
| Thymus |
<1 |
<1 |
<1 |
<1 |
NDc |
ND |
| Mesenteric LN |
<1 |
4.93 |
4.61 |
1.92 |
178.2 |
120.3 |
| Small intestine |
<1 |
<1 |
<1 |
4.27 |
3.87 |
7.38 |
| Large intestine | 1.31 | 2.58 | 4.4 | 2.68 | 1.88 | 12.8 |
a < indicates below the limit of detection; bLN lymph node, cND not done.