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T83 inhibited Jab1 in a dose- and time-dependent manner in NPC cells. Cells from NPC cell lines were treated with and without T83 at the specified concentrations for 24 h (A) or exposed to 2 μM T83 for various time points (B). Expression of Jab1,p53, p27 and β-actin were examined by Western blotting (C). DMSO was used as control in “0” groups.
