Table 3.
The fractions of various subsets of cells among the CD4+ or CD8+ T cells, or CD19+ B cells
| |
Controls (n = 18) |
MS |
|||
|---|---|---|---|---|---|
| Overall (n = 30) | RRMS (n = 17) | SPMS (n = 6) | PPMS (n = 7) | ||
| CD21+ in CD4+ T cells |
0.41 ± 0.34 |
0.77 ± 0.76 |
0.78 ± 0.76 |
0.79 ± 1.09 |
0.70 ± 0.42 |
| CD32+ in CD4+ T cells |
1.06 ± 0.62 |
2.85 ± 3.72 a |
1.68 ± 1.05 |
5.97 ± 7.40 a, b |
2.86 ± 1.65 |
| CD35+ in CD4+ T cells |
5.34 ± 4.74 |
8.73 ± 8.85 |
8.33 ± 5.33 |
5.52 ± 2.15 |
12.36 ± 16.01 |
| CD21+ in CD8+ T cells |
1.16 ± 0.99 |
2.71 ± 1.86 a |
2.07 ± 0.66 |
4.08 ± 3.33 a |
2.92 ± 1.35 |
| CD32+ in CD8+ T cells |
3.05 ± 2.52 |
3.22 ± 3.03 |
1.88 ± 1.82 |
2.98 ± 1.95 |
6.29 ± 3.87 b, c |
| CD35+ in CD8+ T cells |
4.43 ± 1.95 |
5.43 ± 3.38 |
5.65 ± 4.48 |
5.26 ± 1.80 |
5.23 ± 2.48 |
| CD21+ in CD19+ B cells |
84.76 ± 9.66 |
87.51 ± 6.67 |
88.13 ± 6.69 |
86.07 ± 8.20 |
87.05 ± 5.37 |
| CD32+ in CD19+ B cells |
70.02 ± 13.77 |
66.46 ± 15.42 |
63.39 ± 16.65 |
65.90 ± 14.42 |
74.41 ± 11.67 |
| CD35+ in CD19+ B cells | 94.43 ± 4.90 | 92.63 ± 5.06 | 93.61 ± 4.58 | 92.27 ± 1.97 | 90.57 ± 7.55 |
Data are presented as mean percentage ± SD.
aP < 0.05 compared to control subjects.
bP < 0.05 compared to RRMS.
cP = 0.051 compared to control subjects.