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. 2013 Jul 9;8(7):e69304. doi: 10.1371/journal.pone.0069304

Figure 4. Mutation of NEDD9Y189 stimulates faster adhesion dynamics.

Figure 4

A. Time-lapse microscopy of the assembly and disassembly of GFP-positive focal adhesions. Shown are examples of focal adhesions in NEDD9−/− MEFs transfected with GFP.NEDD9, GFP.NEDD9Y189F and GFP.NEDD9 Y214F. Each box shows a 4.7 µm×4.7 µm cropped region. Arrows point to each adhesion at the time of peak fluorescence intensity. B. Focal adhesion assembly rate constants (k) for the indicated fusion proteins. C. As for B, except data showing the disassembly rate constants (k). N>25 individual adhesions were analysed per condition. *p<0.05, N.S. = not significant.