Figure 4. Effect of VEGF-Trap combined with gemcitabine on cell apoptosis within tumors.

(A) Cell apoptosis was evaluated by TUNEL staining, the representative sections of LLC tumor tissues were obtained from mice on day 15 after treatment initiation; (B) The apoptotic index was determined as described in “Materials and methods”. *P<0.05, **P<0.01 vs the control group. Scale bar, 50 µm.