Table 2. Association between cytoplasmic FOXO1 and pFOXO1 expression and clinico-pathological parameters.
Variables | N | High Cystoplasmic FOXO1 expression | P-value | High Cytoplasmic pFOXO1 expression | P-value | ||
Number (%) | Odds ratio (95%CI) | Number (%) | Odds ratio (95%CI) | ||||
Age (Years) | |||||||
≤50 | 102 | 40 (39.2%) | 1 | 0.001 | 39 (38.2%) | 1 | 0.066 |
>50 | 79 | 50 (63.3%) | 2.67 (1.46–4.90) | 41 (51.9%) | 1.74 (0.96–3.16) | ||
Gender | |||||||
Male | 124 | 57 (46.0%) | 1 | 0.136 | 55 (44.4%) | 1 | 0.980 |
Female | 57 | 33 (57.9%) | 1.62 (0.86–3.05) | 25 (43.9%) | 0.98 (0.52–1.84) | ||
Seisure | |||||||
No | 149 | 77 (51.7%) | 1 | 0.257 | 67 (45.0%) | 1 | 0.654 |
Yes | 32 | 13 (40.6%) | 0.64 (0.30–1.39) | 13 (40.6%) | 0.84 (0.39–1.82) | ||
IICP | |||||||
No | 112 | 50 (44.6%) | 1 | 0.082 | 52 (46.4%) | 1 | 0.442 |
Yes | 69 | 40 (58.0%) | 1.71 (0.93–3.14) | 28 40.6%) | 0.79 (0.43–1.45) | ||
MTD | |||||||
<5 cm | 80 | 42 (52.5%) | 1 | 0.506 | 34 (42.5%) | 1 | 0.682 |
≥5 cm | 101 | 48 (47.5%) | 0.82 (0.46–1.48) | 46 (45.5%) | 1.13 (0.63–2.04) | ||
WHO grade | |||||||
II | 61 | 21 (34.4%) | 1 | 0.001 | 21 (34.4%) | 1 | 0.102 |
III | 27 | 10 (37.0%) | 1.12 (0.44–2.88) | 11 (40.7%) | 1.31 (0.52–3.33) | ||
IV | 93 | 59 (63.4%) | 3.30 (1.68–6.50) | 48 (44.2%) | 2.03 (1.04–3.96) |
Abbreviations: IICP, increased intracranial pressure; MTD, mean tumor diameter.