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. 2013 Jul 9;8(7):e69259. doi: 10.1371/journal.pone.0069259

Table 1. Clinicopathological characteristics of the patients (n = 141).

SYSUCC LZECH FAHXU
Variable No. (% of n) No. (% of n) No. (% of n) p
Gender
Male 58 (82.9) 39 (63.9) 10 (100) 0.007
Female 12 (17.1) 22 (36.1) 0 (0.0)
Age (yrs)
<60 44 (62.9) 38 (62.3) 7 (70.0) 0.894
≥60 26 (37.1) 23 (37.7) 3 (30.0)
Tumor location
Upper third 8 (11.4) 6 (9.8) 0 (0) 0.306
Middle third 41 (58.6) 44 (72.1) 6 (60.0)
Lower third 21 (30.0) 11 (18.0) 4 (40.0)
Tumour length (cm)a
<5 cm 12 (30.8) 18 (29.5) 3 (0) 0.991
≥5 cm 27 (69.2) 43 (70.5) 7 (70.0)
AJCC stage
I 1 (1.4) 4 (6.6) 0 (0) 0.315
II 27 (38.6) b 18 (29.5) 2 (20.0)
III 42 (60.0) c 39 (63.9) 8 (80.0)
Pathology
Pure SC 64 (91.4) 48 (78.7) 8 (80.0) 0.111
Mixed SC 6 (8.6) 13 (21.3) 2 (20.0)
LV invasiona
Yes 29 (74.4) 46 (75.4) 4 (40.0)
No 10 (25.6) 15 (24.6) 6 (60.0)
Treatment
S 19 (27.1) 20 (32.8) 3 (30.0) <0.001
S+C 17 (24.3) 27 (44.3) 3 (30.0)
S+R 1 (1.4) 8 (13.1) 0 (0)
S+C+R 2 (2.9) 6 (9.8) 4 (40.0)
C+R 20 (28.6) - -
C 11 (15.7) - -
Surgical outcomea
R0 38 (97.4) 57 (93.4) 10 (100.0) 0.594
R1 1 (2.6) 1 (1.6) 0 (0)
R2 0 (0) 3 (4.9) 0 (0)

SYSUCC, Sun Yat-sen University Cancer Center; LZECH, Linzhou Esophageal Cancer Hospital; FAHXU, the First Affiliated Hospital of Xiamen University; AJCC, American Joint Committee on Cancer; SC, small cell; LV, lymphovascular; S, surgery; C, chemotherapy; R, radiotherapy. afor the patients with surgical resection (n = 110); bincluding 18 cases of pathological staging with surgical resection, 9 cases of clinical staging with non-surgical resection; c including 20 cases of pathological staging with surgical resection, 22 cases of clinical staging with non-surgical resection.