Table 4. Factors that affect the overall survival by multivariate Cox regression analysis for the entire cohort of patients (n = 141).
| Variable | Relative risk | 95% CI | p | ||
| Upper | Lower | ||||
| Sex | |||||
| Male | 1 | 0.144 | |||
| Female | 0.647 | 0.361 | 1.160 | ||
| Age (yrs) | |||||
| <60 | 1 | 0.380 | |||
| ≥60 | 1.233 | 0.772 | 1.970 | ||
| Tumour length | |||||
| <5 cm | 1 | 0.067 | |||
| Others a | 1.734 | 0.962 | 3.126 | ||
| AJCC stage | |||||
| I+II b | 1 | 0.003 | |||
| III | 2.080 | 1.292 | 3.349 | ||
| Tumor location | |||||
| Upper third | 1 | 0.765 | |||
| Middle third | 0.813 | 0.401 | 1.649 | ||
| Lower third | 0.740 | 0.330 | 1.659 | ||
| Pathology | |||||
| Pure SC | 1 | 0.035 | |||
| Mixed SC | 0.459 | 0.222 | 0.946 | ||
| LV invasion | |||||
| No | 1 | 0.865 | |||
| Yes | 1.054 | 0.608 | 1.825 | ||
| NA | 0.877 | 0.467 | 1.649 | ||
| Treatment | |||||
| S+C+R | 1 | 0.587 | |||
| Others | 1.272 | 0.534 | 3.032 | ||
AJCC, American Joint Committee on Cancer; SC, small cell; LV, lymphovascular; NA, not available; S, surgery; C, chemotherapy; R, radiotherapy.
a
including the tumours ≥5 cm in length and those not available for tumour length;
b
only five cases were with stage I.