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. 2013 Jul 9;8(7):e67805. doi: 10.1371/journal.pone.0067805

Table 2. Lipids, lipoproteins and metabolic markers according to LIPC genotypes and case-control design.

Cases Controls
p value forcase-controleffect p value forLIPCeffect
CC CT TT CC CT TT
Numbers of subjects 322 196 39 356 192 12
TC (g/L) 1.99 (0.43) 2.05 (0.38) 2.08 (0.52) 2.22 (0.35) 2.29 (0.41) 2.35 (0.51) 0.001 0.03
HDLc (g/L) 0.43 (0.12) 0.43 (0.14) 0.44 (0.10) 0.55 (0.12) 0.56 (0.14) 0.62 (0.12) 0.001 0.31
LDLc (g/L) 1.25 (0.37) 1.27 (0.34) 1.31 (0.48) 1.45 (0.32) 1.47 (0.35) 1.49 (0.42) 0.001 0.40
TG (g/L)* 1.62 (0.96) 1.77 (0.91) 1.73 (0.91) 1.13 (0.61) 1.30 (1.02) 1.33 (0.74) 0.001 0.02
Apo A-1 (g/L) 1.22 (0.21) 1.23 (0.25) 1.27 (0.18) 1.51 (0.23) 1.52 (0.25) 1.68 (0.21) 0.001 0.07
Apo B (g/L) 1.04 (0.23) 1.07 (0.22) 1.10 (0.32) 1.09 (0.21) 1.13 (0.22) 1.13 (0.28) 0.001 0.04
Apo E (g/L)* 99.6 (59.3) 108.5 (61.4) 100.7 (71.9) 72.3 (42.3) 79.7 (55.2) 67.1 (43.8) 0.001 0.12
Apo C3 (g/L)* 32.3 (12.5) 34.3 (12.8) 39.6 (23.5) 30.2 (11.9) 31.5 (14.7) 35.8 (16.8) 0.001 0.009
Glycaemia (g/L)* 1.11 (0.41) 1.06 (0.35) 1.10 (0.45) 0.97 (0.17) 0.99 (0.20) 1.00 (0.19) 0.001 0.86
Insulin (IU/L)* 16.1 (21.3) 14.9 (23.6) 23.1 (38.5) 9.5 (6.8) 10.5 (7.8) 10.8 (6.9) 0.001 0.37
HOMA-IR* 4.9 (11.8) 4.1 (6.5) 6.5 (10.9) 2.4 (2.1) 2.7 (2.7) 2.8 (2.3) 0.001 0.45
Adiponectin (mg/L) 5.8 (4.2) 6.0 (5.1) 6.0 (4.6) 7.2 (4.9) 6.6 (3.9) 4.8 (3.3) 0.001 0.62
Metabolic syndrome (NCEP-ATPIII) 52.8% 46.9% 48.7% 16.3% 17.7% 16.6% 0.001 0.72
*

Analyses were performed on log transformed data.