Table 5. Risk for ankle-brachial index <0.90 according to LIPC genotypes in CAD patients.
| OR | 95% CI | p3 | |
| Unadjusted | |||
| CT vs CC | 1.50 | 1.03–2.19 | 0.03 |
| TT vs CC | 1.97 | 0.92–3.65 | 0.09 |
| CT and TT vs CC | 1.55 | 1.08–2.22 | 0.02 |
| Adjusted1 –2 | |||
| CT vs CC | 1.52 | 1.03–2.25 | 0.036 |
| TT vs CC | 1.71 | 0.84–3.48 | 0.14 |
| CT and TT vs CC | 1.55 | 1.07–2.25 | 0.036 |
1
Adjusted for smoking, diabetes, physical activity and heart rate.
All interactions between ankle-brachial index, LIPC genotypes and variables of adjustment were non-significant.
2
Area under the curve (AUC) for adjusted model: 0.73, corrected AUC after bootstrap validation: 0.72.
3
False discovery rate method was used to correct for multiple comparisons for subgroup analyses. Corrected p values are shown.