Skip to main content
. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Liver Int. 2013 Apr 1;33(7):1044–1055. doi: 10.1111/liv.12164

Figure 1. Gliotoxin treatment during early liver regeneration induces apoptosis of HSCs and inhibits proliferation.

Figure 1

(A) Schematic of the early-stage gliotoxin study, in which rats were treated with DMSO or 3mg/kg gliotoxin, followed by a second dose 24 hours later at the time of PH. Livers were harvested 24 hours following treatment. (B) H&E staining in control and gliotoxin-treated livers (arrows point to mitotic figures; 200X). (C) Ki67 and TUNEL staining in control and gliotoxin-treated groups.