Table 1. Characteritics of the 8 recipients.
Recipient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Date of sample collection | 2/12/2002 | 3/25/1998 | 01/02/1999 | 6/26/2000 | 3/1/1999 | 4/18/2007 | 6/16/1999 | 10/24/2008 |
Estimated time since infection (days) | 33 | 37 | 37 | 40 | 43 | 85 | 32 | 38 |
HIV-1 RNA (log10 copies/mL) | 5.93 | 4.70 | 4.44 | 5.52 | 6.07 | 4.01 | 4.83 | 4.62 |
HIV-1 DNA (log10 copies/10e6 PBMC) | 3.25 | 3.12 | 3.15 | 2.86 | 3.64 | 2.76 | 3.84 | ND |
CD4 cell count (cells/mm3) | 520 | 734 | 368 | 681 | 381 | 635 | 558 | 523 |
Viral subtype | B | B | B | B | B | B | B | B |
Viral resistance | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age (years) | 38 | 28 | 36 | 21 | 28 | 39 | 29 | 19 |
Gender (male/female) | M | M | F | M | F | M | M | F |
Risk group | Het | MSM | Het | MSM | Het | MSM | MSM | Het |
Country of birth | France | Chile | France | France | Algeria | France | France | France |
Living place | France | France | France(West Indies) | France (West Indies) | France | France | France | France (West Indies) |
Number of regular sexual partners * | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 |
Number of casual sexual partners * | 0 | 15 | 0 | 0 | 0 | 5 | 3 | 0 |
Serological syphilis testing | – | – | – | – | – | – | – | – |
HBV testing | ||||||||
HBsAg | – | – | – | – | – | – | – | – |
HBsAb | – | + | – | – | – | + | – | – |
HBcAb | – | + | – | – | – | – | – | – |
HBV DNA (log10 IU/mL) | n.d. | Und. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. |
HCV testing | ||||||||
HCV Ab | – | + | – | – | – | – | – | – |
HCV RNA (log10 IU/mL) | n.d. | 1.7 | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. |
Prior sexually transmitted infections § | Condyloma | No | Vaginal candidiasis | No | No | No | Condyloma | No |
In the 6 months preceding PHI diagnosis.
Urethritis, rectitis, genital herpes infection, vulvo-vaginal candidosis, condyloma and/or syphilis.
PBMC = peripheral blood mononuclear cells; Het = heterosexual; MSM = man having sex with men; HBV = hepatits B virus; HBsAg = HBV surface antigen; HBsAb = HBV surface antibodies; HBcAb = HBV core antibodies; HCV = hepatitis C virus; n.d. = not done; und = undetectable.