. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Mol Psychiatry. 2013 Feb 26;19(3):302–310. doi: 10.1038/mp.2013.9

Table 4.

Amphetamine-induced change in [¹¹C]raclopride BP_ND and dialysate DA in striatum

Amphetamine Dose	Animal	PET Baseline BPND	AMPH BPND	Δ BP	Microdialysis Baseline DA^* (nM)	Δ Peak DA (%)	Δ Average DA (%)
0.5 mg/kg	D	3.48	1.87	−46%	-	-	-
PET: n=2experiments/2 animals	D	-	-	-	8.81	5167	2355
MD: n=5 experiments/2 animals	D	-	-	-	8.36	4688	2819
	E	3.12	2.26	−27%	-	-	-
	E	-	-	-	13.14	2981	2169
	E	-	-	-	28.83	2473	1673
	E	-	-	-	24.05	913	401
Mean +/− SD		3.30 ± 0.25	2.07 ± 0.28	−36.8% ± 13.3%	16.64 ± 9.29	3244 ± 1723	1884 ± 925

MD- Microdialysis; AMPH- Amphetamine

Mean values of n= 3 to 4 baseline dopamine samples from −30 to 0 minutes before amphetamine