Table 1.
Clinical summary for ten cases of Clostridium difficile infection (CDI) in the Specialized Hospital of Lung Diseases and Tuberculosis (SHLDT) in Bystra, South Poland
| Date of hospitalization | Age (years)/sex/number of strain | Unit | Underlying diseases | Anti-TB drugs | Other AB | Date of diagnostic CDI | Symptoms of CDI | Fatality associated with CDI | PCR ribotype/rifampicin RI (R) or RI (S) |
|---|---|---|---|---|---|---|---|---|---|
| 27.11.09–17.12.09 | 82/F/CD14 | TBU | Non-active TB, atherosclerosis, hypertension | – | AMOX | 09.12.09 | Diarrhea, hypovolemic shock, extreme dehydration | Yes | 046/RI (R) |
| 13.10.09–04.01.10 | 86/F/CD12 | TBU | AP TB, chronic congestive heart diseases | RI, I | CI | 09.12.09 | Recurrent diarrhea, heart failure (associated with CDI) | Yes | 046/RI (R) |
| 03.11.09–08.01.10 | 80/F/CD15 | TBU | AP TB, failure, chronic obstructive pulmonary | RI, I, P | – | 11.12.09 | Diarrhea | – | 046/RI (R) |
| 19.11.09–02.02.10 | 48/M/CD13 | TBU | AP TB, alcoholism, cirrhosis of the liver | RI, I, P | – | 09.12.09 | Recurrent diarrhea, neurological symptoms (associated with CDI) | Yes | 046/RI (R) |
| 17.02.09–09.04.10 | 67/F/CD18 | TBU | AP TB, lung empyema, cirrhosis of the liver | RI, I, P | – | 30.12.09 | Recurrent severe diarrhea | Yes | 046/RI (R) |
| 19.11.09–12.02.10 | 51/M/CD4 | TBU | AP TB, pulmonary mycetoma | RI, I, P | CI | 12.01.10 | Diarrhea | – | 046/RI (R) |
| 04.02.10–03.03.10 | 86/M/CD22 | INT | Respiratory systems diseases | – | AMOX, CI | 25.02.10 | Diarrhea | – | 046/RI (R) |
| 17.03.10–25.03.10 | 72/MCD30 | PUL | Pneumonia, lung empyema | – | AMOX, CI, CM, MZN | 22.03.10 | Severe diarrhea | Yes | 017/RI (R) |
| 29.11.10–05.02.11 | 88/M/CD61 | PUL | Pneumonia, chronic obstructive pulmonary renal failure | – | AMOX, TX | 30.12.10 | Diarrhea | – | 001/RI (S) |
| 14.09.10–23.09.10 | 69/M/CD50 | TS | Lung tumor | – | CEF | 23.09.10 | Diarrhea | – | 002/RI (S) |
AB antibiotics, CDI C. difficile infection, TBU tuberculosis unit, INT internal unit, PUL pulmonology, TS thoracic surgery, TB tuberculosis, AP TB active pulmonary tuberculosis, RI rifampicin, I isoniazid, P pyrazinamide, AMOX amoxicillin, CI ciprofloxacin, CM clindamycin, MZN metronidazole, TX trimethoprim/sulfamethoxazole, CEF cefazolin (perioperative prophylaxis), RI (R) rifampicin resistant, RI (S) rifampicin sensitive