Table 1.
Subject characteristics and baseline values of markers of calcium, phosphate and bone metabolism
| Pregnant | Lactating | Non-pregnant, non-lactating | |
|---|---|---|---|
| n = 10 | n = 10 | n = 10 | |
| Subject characteristics | |||
| Age (years) | 29.7 ± 2.2 | 27.3 ± 2.0 | 27.6 ± 2.2 |
| Weight (kg) | 62.5 ± 3.6 | 59.4 ± 2.8 | 55.8 ± 2.4 |
| Height (m) | 1.62 ± 0.02 | 1.65 ± 0.01 | 1.59 ± 0.02 |
| Parity | 4.6 ± 0.8 (1–8)1 | 3.6 ± 0.78 (1–7)1 | 3.0 ± 0.9 (0–7)1 |
| Gestation/post-partum (weeks) | 32.6 ± 0.5 | 14.2 ± 0.20 | − |
| pCr(mmol/L) | 59.2 ± 1.5NL | 70.3 ± 2.9 | 74.0 ± 2.5 |
| pAlb (g/L) | 25.5 ± 0.8NL | 36.7 ± 0.91 | 34.1 ± 0.65 |
| Hb (g/L) | 11.2 ± 0.38NL | 13.2 ± 0.57 | 13.0 ± 0.35 |
| p25(OH)D (nmol/L) | 59.7 ± 3.8 | 63.2 ± 5.1 | 70.4 ± 4.6 |
| Markers of renal mineral handling | |||
| TmCa/GFR (mmol/L GFR) | 2.31 ± 0.20 | 2.39 ± 0.15 | 2.15 ± 0.15 |
| TmP/GFR (mmol/L GFR) | 1.25 ± 0.06 | 1.42 ± 0.08 | 1.18 ± 0.09 |
Values are given as mean ± SE or when indicated1 as range (min–max)
Cr creatinine, Hb haemoglobin, 25(OH)D 25(OH) vitamin D, p plasma, TmCa/GFR the renal calcium threshold, TmP/GFR the renal threshold for phosphate
Letters are used to indicate significant between-group differences in baseline values as tested by ANOVA/Scheffé (P ≤ 0.05); N significantly different to non-pregnant and non-lactating women; L significantly different to lactating women