Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Feb 5;5(2):15. doi: 10.1186/gm419

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Lechner et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Validation of consistent hypermethylated methylation variable positions (hyper-MVPs) in E6 and E6&E7 infected cell-line clones. (A) The formalin-fixed, paraffin wax-embedded (FFPE) hyper-MVP signature consistent with E6 (infected with E6 or E6&E7) versus empty vector controls (Monte Carlo P= 0.007). Volcano plot shows t-statistics of E6 versus empty clones plotted against log₁₀FFPE P values. (B) Heat-map representation of consistent hyper-MVPs in clones infected with E6, E6&E7, or E7 and empty vector controls. Yellow indicates relative hypomethylation in HPV+ samples and blue indicates hypermethylation (MVPs normalized across samples).