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. 2013 Jun 4;4(3):59. doi: 10.1186/scrt215

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Copyright © 2013 Du et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Hepatocyte growth factor (HGF) expression in injured kidney tissues at 1 week after intervention. (A) Representative micrographs illustrating HGF expression in injured kidney tissues. The overwhelming majority of positive staining resided in tubular cells. HGF staining in tubular cells was substantially intensified in cases of cell injection or nephrectomy. (a) through (c) Magnification ×200; (d) through (i) Magnification ×400. (B) Representative micrographs illustrating human HGF expression in injured kidney tissues. No positive-staining TECs were identifiable in kidney sections from sham-operated animals or IRI animals receiving vehicle injection (data not shown). By contrast, at 1 week after injection, positive staining (black arrows) was detected in kidney sections from cell-injected animals, mostly residing in cytoplasm of tubular cells. (a) Magnification ×100; (b) and (c) Magnification ×400.