Table 2.

LH Regulated Genes That Are Differentially Expressed Between aGCs and mGCs

Gene Name or Chromosomal Location	Gene Symbola	Fold Change Between LH Response of aGCs vs mGCs	P Value	LH Regulated in aGCs fdr < 0.01	LH Regulated in mGCs fdr < 0.01	HSI − Mean RMA Hybridization Value Before LH		HSI − Mean RMA Hybridization Value After LH
						aGC	mGC	aGC	mGC
Nidogen 2	NID2	16.52	.002	Yes	Yes	23	558	3616	5224
Similar to Collagen α-1(XIV) chain precursor	LOC781493	8.91	.001	Yes	No	14	138	371	417
Caveolin 1	CAV1	7.54	.001	Yes	Yes	16	75	6548	6235
Fibronectin 1	FN1	5.10	.002	Yes	No	89	744	1200	1978
Claudin 11	CLDN11	4.91	.011	Yes	Yes	12	57	3518	3409
Dickkopf homolog 3	DKK3	4.77	.001	Yes	Yes	15	92	2273	2952
Collagen, type V, α 2	COL5A2	3.82	.029	Yes	No	15	256	215	956
CART prepropeptide	CARTPT	3.68	.001	No	Yes	45	155	46	43
Chr2:110382-336-110382643(−)	(IGFBP5)	3.67	.033	Yes	No	71	540	573	1181
Dihydropyrimidinase-like 3	DPYSL3	3.56	.001	Yes	YES	21	81	252	277
ρ family GTPase 3	RND3	3.55	.001	Yes	Yes	29	93	4046	3710
ADAM metallopeptidase with thrombospondin type 1 motif; 1	ADAMTS1	3.34	.001	Yes	Yes	45	184	1272	1569
Chromosome 8 open reading frame 4	C27H8orf4	3.32	.025	Yes	Yes	11	37	654	662
Cyclin D2	CCND2	−3.01	.002	Yes	Yes	5297	3993	64	146
SPARC-related modular calcium binding 2	SMOC2	−3.02	.015	Yes	No	942	717	192	442
Hydroxysteroid (17-β) dehydrogenase 1	HSD17B1	−3.05	.010	Yes	Yes	2452	1039	49	62
Heme oxygenase 1	HMOX1	−3.07	.033	Yes	No	367	218	90	164
NADH dehydrogenase (ubiquinone) 1 α subcomplex; 4-like 2	NDUFA4L2	−3.10	.005	Yes	No	62	21	20	22
6-Phosphofructo-2-kinase/fructose-2;6-biphosphatase 3	PFKFB3	−3.28	.011	No	Yes	283	95	504	556
Chromosome 12 open reading frame 32	C5H12orf32	−3.35	.002	Yes	No	226	236	32	113
CD14 molecule	CD14	−3.39	.048	No	Yes	77	20	146	130
Neural precursor cell expressed; developmentally down-regulated 9	NEDD9	−3.41	.032	Yes	No	130	118	21	65
KIAA0101 protein (PCNA-assoc factor)	KIAA0101	−3.45	.018	Yes	Yes	1782	1439	45	126
SAM and SH3 domain containing 1	SASH1	−3.51	.028	Yes	No	105	65	16	35
chr2:88862297–88862784 (−)	(Ankrd44)	−4.04	.009	Yes	No	405	163	70	114
chr11:16969669-16970066 (+)	—	−4.26	.006	Yes	Yes	701	267	27	43
Complement component 1; s subcomponent	C1S	−5.63	.005	No	Yes	20	41	18	210
Guanylate cyclase activator 1A (retina)	GUCA1A	−6.07	.008	Yes	No	485	97	21	25
chr1:73033634-73034079 (+)	—	−8.03	.003	No	Yes	19	200	102	1737

^a Gene symbols enclosed in parentheses are probe sets that recognize transcripts with high homology to a named gene in another species.

Chromosomal locations are based on the Cow October 2011 assembly. Dashes reflect negative or down regulated gene.