Figure 3.

Overlap of SNVs identified in four targeted exome sequencing replicates of the same individual's DNA in the Illumina platform. (a) Comparison of identified coding SNPs (cSNPs) within and between sequencing technologies (GAII vs. HiSeq). There is a high percentage of shared identified SNPs both within and between the different technologies. (b) Comparison of identified InDels within and between sequencing technologies. We observe less overlap between the two technologies probably due to a higher rate of false positive InDels.