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. 2013 Jan 7;4(1):4. doi: 10.1186/scrt152

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Copyright © 2013 Tsao et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Myostatin genetic inactivation does not block the multipotent nonmyogenic differentiation capacity of MDSCs. Representative pictures of proliferating MDSCs treated for 2 weeks in differentiation media and subjected to immunocytochemistry for NF-70 (A) and ASMA (B) to detect marker expression of neural cells and myofibroblasts (200×). MDSC, muscle-derived stem cell; WT, wild type (muscle-derived stem cells); KO, myostatin knockout (muscle-derived stem cells); ASMA, α-smooth muscle actin.