Table 5.
Type of Potassium Channel α-subunit | Localization | Disease In Which Serves As Target | ||
---|---|---|---|---|
CNS | Subcellular | Other | ||
KV7.1 | - | - | Heart, kidney, rectum, lung, placenta, cochlea | Arhytmias |
KV7.2 | Brain, ganglia | Axons | Lung, testis, heart, eye, small intestine, breast | Epilepsy |
KV7.3 | Brain, ganglia | Axons, neuronal somata, dendrites | Testis, retina, colon, eye | Epilepsy |
KV7.4 | Brain | Cochlea, vestibular hair cells, placenta | Epilepsy Psychosis |
|
KV7.5 | Brain, ganglia | Neuronal somata, dendrites | Skeletal muscle | Epilepsy |