Table 7.
Antivenom doses and mortality observed in the literature
Countries | Patients (n) | Mean doses (mL [range]) | # deaths (CFR) | Supportive measures* | Reference |
---|---|---|---|---|---|
Guinea |
26 |
25 ml |
4 (15%) |
No |
Group 2 this study |
|
|
[10–60] |
|
|
|
Guinea |
17 |
40 mL |
3 (18%) |
No |
Group 3 this study |
|
|
[40–60] |
|
|
|
India |
28 |
150 mL |
0 |
VS |
[16] |
India |
27 |
600 mL |
3 (11%) |
VS |
[16] |
|
|
[300–1.600] |
|
|
|
Sri Lanka |
87 |
> 100 mL |
5 (6%) |
VS |
[17] |
|
|
[100–200] |
|
|
|
Sri Lanka |
25 |
100 mL |
2 (8%)§ |
VS |
[18] |
|
|
[80–200] |
|
|
|
India |
37 |
150 mL |
11 (22%)* |
VS; AC |
[19] |
Taiwan |
22 |
30 mL |
0 |
VS |
[20] |
|
|
[10–100] |
|
|
|
Papua New Guinea |
139 |
50 mL |
6 (4.3%) |
VS |
[13] |
Papua New Guinea |
31 |
25 mL |
0 |
VS; AC |
[13] |
India |
14 |
60 mL |
1 (7%) |
VS |
[21] |
India |
12 |
120 mL |
0 |
VS |
[21] |
Thailand |
68 |
100 mL |
0 |
VS |
[22] |
India |
86 |
510 mL |
3 (3.5%) |
VS |
[23] |
|
|
[50–1900] |
|
|
|
Papua New Guinea |
156 |
50 mL |
3 (1.9%) |
VS |
[14] |
Vietnam |
42 |
50 mL |
0 |
VS |
[24] |
|
|
[50–100] |
|
|
|
Thailand |
85 |
40 mL |
1 (1%) |
VS |
[25] |
[10–200] |
VS: ventilatory support; AC: anticholinesterase; §the patients died from extensive necrosis; *three patients died before treatment.