Figure 5.

Effect of various doses of camostat on the maximal basal PD. Maximal basal PD was measured predose and 2 h postdose. A, B, and C, Part 1 included camostat 0.200, 0.800, and 1.600 mg and placebo. D, E, and F, Part 2 included camostat 0.005, 0.010, and 0.020 mg and placebo. The Ringers PD by dose (B and E) and change in PD following amiloride perfusion by dose (C and F) for each part of the study are shown. *P < .05; **P < .005; ***P < .001; ^aP = .09; mean ± SEM. See Figure 3 legend for expansion of abbreviation.