Table 1.
Comparison of two groups: with and without crisis at the time of adrenal insufficiency diagnosis.
| Without crisis | With crisis or imminent crisis | P | |
|---|---|---|---|
| Number of patients | 34 | 26 | |
| Age at diagnosis (years) | 39.2 ± 14.7 | 39.0 ± 13.7 | ns |
| F/M ratio (n/female %) | 28/6—82% f | 20/6—78% f | ns |
| Morning cortisol levels (nmol/L) | 116.4 ± 36.9 | 54.5 ± 26.0 | 0.001 |
| Mean levels of ACTH (pmol/L) | 149.1 ± 101.3 | 220.4 ± 136.4 | ns (0.06) |
| Coexistent elements of aps II (%) | 71% | 23% | 0.01 |
| Treatment by endocrinologist in the past (%) | 47% | 7% | 0.01 |
| Time to diagnosis (months) | 5.8 ± 2.8 | 9.1 ± 3.5 | 0.05 |
| Body mass loss (kg) | 7.0 ± 2.8 | 10.2 ± 3.5 | 0.01 |
| Blood sodium concentration (mEq/L) | 134.5 ± 3.7 | 130.7 ± 4.01 | 0.006 |
| Blood potassium concentration (mEq/L) | 4.35 ± 0.3 | 4.9 ± 0.4 | 0.001 |
| Positive 21-OHAbs titers (%) | 82% | 81% | ns |