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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Dev Biol. 2013 May 2;379(2):221–228. doi: 10.1016/j.ydbio.2013.04.025

Figure 2. The limb phenotypes of Gli3Δ701 mutant mice.

Figure 2

(A) The limb phenotypes of adult mice with the genotypes indicated to the left. Gli3Δ701C refers to the conditional allele prior to the deletion of exon 14, while Gli3Δ701 refers to the same allele in the presence of Prx1-Cre. Only left limbs are shown with the anterior at the top and the posterior at the bottom. Note that the Gli3+/Δ701 forelimb appears short and the autopod is oligosyndactylous, while the hindlimb appears normal. The same magnification is applied to all panels. (B) The limb phenotypes of E16.5 embryos with the indicated genotypes. Limb autopods are indicated by arrowheads. An enlargement of the forelimb (FL) and hindlimb (HL) appears two panels to the right. Note the very short limbs with a single (in FL) or seemingly three digits (in HL) in Gli3Δ701 homozygotes.