Table 1.

Hemodynamic parameters in all patients, with or without splenomegaly.

	All patients (n=62) Mean ± SD	No splenomegaly (n=22) Mean ± SD	Splenomegaly (n=39) Mean ± SD	P (Welch’s t- test)
RA pressure (mmHg)	12 ± 7	10 ± 5	13 ± 7	0.08
RV systolic pressure (mmHg)	83 ± 22	85 ± 20	82 ± 23	0.6
RV diastolic pressure (mmHg)	14 ± 10	13 ± 7	15 ± 11	0.39
PA systolic pressure (mmHg)	86 ± 21	87 ± 21	85 ± 22	0.75
PA diastolic pressure (mmHg)	37 ± 11	39 ± 12	37 ± 11	0.61
PA mean pressure (mmHg)	54 ± 14	55 ± 14	53 ± 14	0.66
PAOP (mmHg)	10 ± 4	10 ± 4	10 ± 4	0.96
CO (L/min)	4.1 ± 1.5	3.8 ± 1.4	4.2 ± 1.5	0.28
CI (L/min/m2)	2.2 ± 0.8	2 ± 0.6	2.3 ± 0.8	0.13
PVR (Wood Units)	12 ± 7	13 ± 7	12 ± 7	0.85
TPG (mm Hg)	43 ± 14	44 ± 14	43 ± 14	0.8

CI indicates cardiac index; CO, cardiac output; PA, pulmonary artery; PAOP, pulmonary artery occlusion pressure; PVR, pulmonary vascular resistance; RA, right atrial; RV, right ventricular; TPG, transpulmonary gradient. Splenomegaly was defined by a volume (using Prassopoulos et al.⁹ formula) higher than 95% limit according to the expected spleen volume by height and weight described by Sprogøe-Jakobsen et al.¹¹.