Skip to main content
. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: J Comp Neurol. 2012 Aug 15;520(12):2757–2773. doi: 10.1002/cne.23085

TABLE 2.

Fractional area [%] of organelles in dendrites including afferent synapses of wildtype (wt) and Loa/+ mice.

Organelle wt MV Loa/+ MV Loa/+ RtTg
Mean ±SEM Mean ±SEM Mean ±SEM
Total Cytosol 55.9 59.1 43.0
 Cytosol without polyribosomes 25.1 ±6.3 59.1** ±3.3 25.3 ±4.4
 Cytosol with polyribosomes 30.8 ±0.3 0.0* ±0.0 17.7 ±0.4
Endoplasmic reticulum 8.9 ±3.2 2.15* ±0.2 11.9 ±0.4
Total Mitochondria 10.3 ±0.4 12.5 ±1.5 8.5 ±0.2
 Normal Mitochondria 9.2 ±1.5 3.75* ±0.3 7.5 ±0.1
 “Aged” Mitochondria 1.1 ±1.1 8.75** ±1.2 1.0 ±0.1
Early endosomes 2.8 ±0.4 4.65 ±1.2 4.6 ±1.8
Late endosomes 3.4 ±1.0 1.8* ±0.5 3.2 ±0.2
Multivesicular bodies 2.0 ±1.2 0.25* ±0.2 1.6 ±0.5
Lysosomes 1.6 ±1.6 0.0* ±0.0 2.6 ±1.7
Tubules 1.7 ±0.6 1.9 ±0.5 1.8 ±0.7
Plasma membrane 7.6 ±1.2 8.8 ±0.1 8.8 ±3.3
Synapses 5.8 ±0.5 8.3 ±2.2 13.1 ±1.2
Unidentified 0.0 ±0.0 0.55 ±0.1 0.9 ±0.8
100.0 100.0 100.0

MV, Trigeminal Motor neurons; RtTg, reticulotegmental nucleus.

Major differences in bold:

*

decrease;

**

increase.