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Decreased cell growth induced by DEK knockdown was associated with decreased cyclin A expression. (A) Western blot analysis of a series of cell cycle–related factors showed after silencing DEK in H1299 and A549 cells, protein levels of cyclin A were decreased (p<0.05), but no changes were observed in protein levels of cyclin B or cyclin D1 (p>0.05). (B, C) Densitometric analyses of protein levels normalized against GAPDH. *p<0.05.
