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. 2013 Jul;61(7):529–547. doi: 10.1369/0022155413491269

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Figure 10. — Measurement of CB2R messenger RNA (mRNA) density of lumbar and cervical dorsal root ganglia (DRG) after chronic constriction injury (CCI) and sham operation compared with density in naive animals. Staining intensity was calibrated from 0 to 1 with background (white) level set at 0 and the value of 1 set at black depicting the densest level of DAB reaction product. Mean density of both lumbar and cervical DRG increased significantly at days 3 and 14 after unilateral CCI of the sciatic nerve. All values are reported as mean ± SD. *At both 3 and 14 days after injury, the levels of CB2R mRNA in the ipsilateral lumbar and cervical DRG were significantly higher in comparison with the naive control. We can observe also a strong increase of the signal in the contralateral DRG for both tested periods (p<0.05). ^†Density of ipsilateral DRG was much lower when compared with contralateral ganglia (p<0.05). The changes of the density in sham-operated animals did not significantly increase except for the ipsilateral lumbar DRG (p<0.05).