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. 2013 Jul;61(7):529–547. doi: 10.1369/0022155413491269

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Figure 8. — Detection of CB2R messenger RNA (mRNA) by in situ hybridization in sections of L4–L5 dorsal root ganglia (DRG) from naive (A), chronic constriction injury (CCI) (B–E), and sham-operated (F–I) rats. Bilateral staining for CB2R mRNA was induced in neuronal bodies of all sizes and in satellite glial cell (SGCs; arrows) by unilateral CCI of the sciatic nerve for 3 days (B, C) and 14 days (D, E). In contrast, sections of L4–L5 DRG removed from sham-operated rats after 3 days (F, G) or 14 days (H, I) displayed only moderate or no CB2R mRNA staining in neurons. Higher intensity of CB2R mRNA staining was observed in SGCs predominantly surrounding the large neurons (arrows), especially on day 14 after sham operation. Scale bars = 50 µm.