Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effects of CCR2 deficiency on Notch ligand expression. Quantitative RT-PCR of normoxic and hypoxic lungs from Ccr2−/− mice show significantly decreased Jagged-1 expression; these mice also had significantly increased baseline expression of Jagged-2, Delta-like (DLL)-1, and DLL-4. Expression of Jagged-2 and DLL-4 were further enhanced with hypoxic exposure (n = 5–7 animals per group). *P < 0.05; **P < 0.01; ***P < 0.001.
