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CD39 deletion prevents iNKT cell proliferation after hyperoxia. (A–C) Bromodeoxyuridine (BrdU) proliferation assay for pulmonary iNKT cells in vivo after oxygen exposure. FACS analysis showed that (A and C) wild-type pulmonary iNKT cells proliferate significantly more than do (B and C) CD39-null pulmonary iNKT cells (P < 0.006) after exposure to hyperoxia. All error bars represent the SEM (n = 2 per group).
