. Author manuscript; available in PMC: 2014 Jul 1.

Published in final edited form as: Bioorg Med Chem Lett. 2013 May 7;23(13):3826–3832. doi: 10.1016/j.bmcl.2013.04.080

Table 3.

Effects of additional substitutions on transcription and cytotoxicity in transfected PC-3 Cells^a

Cmpd No	IC₅₀ SRE.L (μM)^a	% inh SRE.L (100 μM)^a	% inh WST-1 (100 μM)^a
8u	4.7	81	4
13	9.2	80	6
12x	21	63	0
12y	7.4	79	15
12z	10	60	0
14	10	63	0
15	ND	37	0
16	31	88	25
17	ND	21	0
18	ND	21	0

Assays and abbreviations defined in Table 1.