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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Immunol. 2013 Jun 3;191(1):434–447. doi: 10.4049/jimmunol.1203176

Figure 11.

Figure 11

Survival curve of Cr1KO, Cr1/2KO, C3KO, and WT mice after infection with S. pneumoniae. Mice were immunized with 1×105 heat-killed S. pneumoniae followed ten days later (0 days on graph) by infection with 1000 CFU of live S. pneumoniae. Cr1KO mice (dotted line) survive infection with S. pneumoniae at the same rate as WT. Cr1/2KO and C3KO mice survive significantly less frequently. (WT n=11, Cr1/2KO n=7, Cr1KO n=7, C3KO n=3;)