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. 2013 Feb 14;121(15):2891–2901. doi: 10.1182/blood-2012-08-451864

Figure 3.

Figure 3

Cultured CD146+ perivascular cells express markers of hematopoietic perivascular niche cells. (A-B) Ex vivo–expanded CD146+ perivascular cells purified from fat and FBM similarly express higher levels of mRNA of perivascular cell markers when compared with MSCs and CD146− cells (n = 2 donors for each tissue). (C-N) Fat and FBM-derived CD146+ perivascular cells similarly and almost exclusively express (C-F) nestin and (G-J) CXCL12 in culture compared with CD146− cells. (K-N) No difference in Lep-R expression was observed between CD146+ and CD146− cells from either fat and FBM (original magnification, ×20). mRNA, messenger RNA.