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(A) Endothelial progenitor cells (EPCs) significantly decrease from baseline only in copper-depleted patients. The bar indicates mean with standard error of measurement; *P < 0.05. (B) Decrease in ceruloplasmin (Cp) corresponds to a decrease in EPCs in majority of copper-depleted patients and an exploratory analysis by molecular subtype. Square indicates luminal; circle, triple-negative; triangle, human epidermal growth factor 2 (HER2)-positive.
