Skip to main content
. Author manuscript; available in PMC: 2013 Oct 12.
Published in final edited form as: Circ Res. 2012 Aug 14;111(9):1176–1189. doi: 10.1161/CIRCRESAHA.112.266395

Figure 8. eNOS overexpression increases adipose tissue mitochondrial energetics.

Figure 8

Extracellular flux (XF) analysis of adipose tissue explants from WT and eNOS-TG mice fed a HFD for 14 wks: (A) Representative photomicrographs of adipose tissue explants used for XF analysis; (B) Oxygen consumption rates (OCR) of adipose tissue explants: After three baseline measurements, antimycin A and rotenone (AA/Rot) were injected to identify the mitochondria-dependent OCR. (C) Mitochondrial OCR calculated from measurements in panel B. (D) Extracellular acidification rate (ECAR) measured from adipose explants; ECAR is a surrogate measure of glycolytic rate. n = 3–4 per group, *p<0.05 vs WT.