FIGURE 4:

SAA and other inflammatory mediators expressed in podocytes exposed to AGE and inhibition by antibody to RAGE. Cells were exposed to (i) control and (ii) AGE-bovine serum albumin (AGE-BSA, 300 µg/mL), with and without the anti-RAGE antibody or control serum for 1 day. Expression of mRNA was determined by real-time RT–PCR and displayed relative to control (no addition). Data are expressed as mean ± SD. *P < 0.05 versus control (no addition), ^†P < 0.05 versus AGE with control serum. n = 5–6.