Table 1.
Glucose (mg/dL) |
Body weight (g) |
Kidney/body (mg/g) | Blood pressure (mmHg) systolic/diastolic | |||
---|---|---|---|---|---|---|
Baseline | Week 20 | Baseline | Week 20 | Week 20 | Week 20 | |
Controls | ||||||
Standard chow | 180 ± 27 | 167 ± 23 | 19.3 ± 1.4 | 29.6 ± 2.6 | 6.17 ± 0.60 | 139 ± 27/107 ± 23 |
High-protein chow | 215 ± 19 | 172 ± 23 | 19.6 ± 0.7 | 30.2 ± 1.9 | 6.26 ± 0.69 | 123 ± 14/102 ± 14 |
Diabetic | ||||||
Standard chow | 187 ± 31 | 435 ± 131* | 21.0 ± 1.0 | 25.6 ± 2.4* | 8.43 ± 1.84* | 146 ± 16/116 ± 16 |
High-protein chow | 204 ± 31 | 497 ± 88.0* | 20.0 ± 0.9 | 24.3 ± 1.9* | 10.32 ± 1.36*,** | 152 ± 18***/123 ± 18*** |
*P < 0.001 compared with control in each diet group.
**P = 0.021 kidney/body weight compared with diabetic standard chow.
***P = 0.005 blood pressure compared with control on high-protein chow.